Works before independent research

33: Gaolin Liang, Hongjun Ren, and Jianghong Rao*. A biocompatible condensation reaction for controlled assembly of nanostructures in living cells. Nature chemistry. 2010, 2: 54-60. (DOI: 10.1038/NCHEM.480)

32: Anca Dragulescu-Andrasi, Gaolin Liang, and Jianghong Rao. "In vivo Bioluminescence Imaging of furin activity in breast  cancer cells using bioluminogenic substrates" Bioconjugate Chemistry. 2009, 20: 1660-1666. ( DOI:10.1021/bc9002508)

31: Gaolin Liang, Zhimou Yang, Rongjun Zhang, Lihua Li, Yijun Fan, Yi Kuang, Yuang Gao, Ting Wang, W William Lu, and Bing Xu. "Supramolecular hydrogel of a D-aminoacid dipeptide for controlled drug release in vivo" Langmuir. 2009, 25(15): 8419-8422. (DOI: 10.1021/la804271d)

30: Cheng Yang, Gaolin Liang, Keming Xu, Ping Gao, and Bing Xu. "Bactericidal functionalization of wrinkle-free fabrics via covalently bonding TiO2@Ag nanoconjugates" Journal of Materials Science. 2009, 44(7): 1894-1901.

29: Jinhao Gao, Gaolin Liang, Jerry S Cheung, Yue Pan, Yi Kuang, Fan Zhao, Bei Zhang, Xixiang Zhang, Ed X Wu, and Bing Xu. "Multifunctional yolk-shell nanoparticles: A potential MRI contrast and anticancer agent" Journal of the American Chemical Society. 2008, 130(35): 11828-11833. (DOI: 10.1021/ja803920b)

28: Kejun Cheng, Gaolin Liang, Changqi Hu. "Acid-catalyzed epimerization of Kobophenol A to Carasinol B" Molecules. 2008, 13(4): 938-942.

27: Keming Xu, Weiwei Ge, Gaolin Liang, Ling Wang, Zhimou Yang, Qigang Wang, I-Ming Hsing, and Bing Xu*. "Bisphosphonate-containing supramolecular hydrogels for topical decorporation of uranium-contaminated wounds in mice" International Journal of Radiation Biology. 2008, 84(5): 353-362.

26: Zhimou Yang, Gaolin Liang, and Bing Xu* "Enzymatic hydrogelation of small molecules" Accounts of Chemical Research. 2008, 41(2): 315-326. (DOI: 10.1021/ar7001914)

25: Gaolin Liang, Keming Xu, Lihua Li, Liang Wang, Yi KuangY, Zhimou Yang, and Bing Xu* "Using Congo red to report intracellular hydrogelation resulted from self-assembly of small molecules" Chemical Communications. 2007, 4096-4098. (DOI: 10.1039/B712971H)

24: Zhimou Yang, Gaolin Liang, Zufeng Guo, Zhihong Guo, and Bing Xu* "Intracellular Hydrogelation of Small Molecules Inhibits Bacterial Growth" Angewandte Chemie-International Edition. 2007, 46(43) 8216-8219. (DOI:10.1002/anie.200701697)

23: Zhimou Yang, Gaolin Liang, Manlung Ma, Yuan Gao, and Bing Xu* "In Vitro and In Vivo Enzymatic Formations of Supramolecular Hydrogels Based on Self-Assembled Nanofibers of a beta-Amino Acid Derivative" Small. 2007, 3(4): 558-562. (DOI: 10.1002/small.200700015)

22: Zhimou Yang, Gaolin Liang, and Bing Xu* "Enzymatic Control of the Self-Assembly of Small Molecules: A New Way to Generate Supramolecular Hydrogels" Soft Matter. 2007, 3: 515-520. (Highlight) (DOI: 10.1039/B700138J)

21: Zhimou Yang, P. L. Ho, Gaolin Liang, K. H. Chow, Qigang Wang, Yang Cao, Zhihong Guo, and Bing Xu* "Using beta-Lactamase to Trigger Supramolecular Hydrogelation" Journal of the American Chemical Society. 2007, 129(2): 266-267. (DOI: 10.1021/ja0675604)

20: Jinhao Gao, Gaolin Liang, Bei Zhang, Yi Kuang, Xixiang Zhang, and Bing Xu* "FePt@CoS2 Yolk-shell Nanocrystals as A Potent Agent to Kill HeLa Cells" Journal of the American Chemical Society. 2007, 129(5): 1428-1433. (DOI: 10.1021/ja067785e)

19: Zhimou Yang, Gaolin Liang, Manlung Ma, A. Sunny Abbah,  William Lu, and Bing Xu* "D-glucosamine-based supramolecular hydrogels to improve wound healing" Chemical Communications. 2007, 843-845. (DOI: 10.1039/B616563J)

18: Zhimou Yang, Gaolin Liang, Manlung Ma, Yuan Gao, and Bing Xu* "Conjugates of naphthalene and dipeptides confer molecular hydrogelators with high efficiency of hydrogelation and superhelical nanofibers" Journal of Materials Chemistry. 2007, 17, 850-854. (DOI: 10.1039/B611255B)

16: Gaolin Liang, Ling Wang, Zhimou Yang, Hokee Koon, Naiki Mak, Chi K Chang*, and Bing Xu* "Using enzymatic reaction to enhance photodynamic therapy effect of porphyrin dityrosine phosphates" Chemical Communications. 2006, 5021-5023. (DOI: 10.1039/B611557H)

15:  Zhimou Yang, Gaolin Liang, Ling Wang, and Bing Xu. Using a Kinase / hosphatase Switch to Regulate a Supramolecular Hydrogel and Forming the Supramolecular Hydrogel in Vivo. Journal of the American Chemical Society. 2006, 128(9): 3038-3043. (DOI: 10.1021/ja057412y)

14: Zhimou Yang, Gaolin Liang, and Bing Xu. Supramolecular hydrogels based on beta-amino acid derivatives. Chemical Communications. 2006, 738-740. (DOI: 10.1039/B516133A)

13: Gaolin Liang, Jingbo Bi, Qinghong Huang, Su Zhang, Changqi Hu. Metabolites and the pharmacokinetics of kobophenol A from Caragana sinica in rats. Journal of Ethnopharmacology. 2005, 101 (3): 324-329.

12: Gaolin Liang, Tong Zhang, Jingmei Wang, Buyun Chen, Kejun Cheng, and Changqi Hu. X-ray single crystal analysis of (-)-(S)-equol from rats' feces fed the phytoestrogen daidzin. Chemistry & Biodiversity. 2005, 2 (7): 959-963.

11: Gaolin Liang, Lisheng Qian, Yiling Cui, and Changqi Hu. Formation of oxidative metabolite from kobophenol A by human intestinal bacterium Klebsilla pneumoniae. Chemistry & Biodiversity. 2005, 2 (4): 506-509.

10: Fusheng Zhou, Weidong Tang, Qin Mu, Guoxun Yang, Yang Wang, Gaolin Liang, Liguang Lou. Semisynthesis and antitumor activities of new styryl-lactone derivatives. Chemical and Pharmaceutical Bulletin. 2005, 53(11): 1387-1391.

9: Buyun Chen, Gaolin Liang, Qichun Mei. Isolation and identification of two effective compositions from the roots of Cargana sinica and study on its physiological activities . Fudan University Journal of Medical Sciences. 2005, 32 (6): 721-724.

8: Gaolin Liang, Kejun Cheng, Hong Zhou and Changqi Hu. Koboquinone A and B, New Metabolites of Kobophenol A in Rats. Chemical and Pharmaceutical Bulletin. 2004, 52(12): 1489-1491.

7: Gaolin Liang, Yanhua Yu and Zhiming Chen. Synthesis of 3,3,10,10- Teramethyl -4,9-Diazadodecan-2,11-Dione Dioxime. Chinese Journal of Pharmaceuticals. 2003, 34(10):492-493.

6: Gaolin Liang, Yanhua Yu, Zhiming Chen, et al. Synthesis of Methylenediphosphonic Acid. Chinese Journal of Modern Applied Pharmaceuticals. 2002, 19(3): 212-213.

5: Gaolin Liang, Mingyang Hu, Yanhua Yu. Synthesis of Etifenin. Chinese Journal of Modern Applied Pharmaceuticals. 2001, 18(2): 117-118.

4: Gaolin Liang, Mingyang Hu, Bocheng Wang. Synthesis of Disodium 3-Amino-1- Hydroxy- Propilidene- 1,1-Diphosphonate. Chinese Journal of Modern Applied Pharmaceuticals. 1999, 16(2): 37-38.

3: Rongjun Zhang, Jian Jin, Gaolin Liang, Weixing Wan, et al. Preparation and preclinical studies of a hepatic receptor imaging agent. Nuclear Science and Techniques. 1998, 9(3):189-192.

2: Gaolin Liang, Jian Jin, Mingyang Hu, et al. Synthesis of Sialoglycoprotein. Chinese Journal of Pharmaceuticals. 1998, 29(6): 248-249.

1: Gaolin Liang, Mingyang Hu, Jian Jin. Synthesis of Cyanomethyl 1-Thioglycoside, Precusor of Liver galactose  Receptor Imaging Agent. Chinese Journal of Pharmaceuticals. 1997, 28(1): 37-38.



Works after independent research
2024
201. Rui Wang, Lei Zhou, Yueyan Yang, Furong Zhao, Xianbao Sun, Xiaoyang Liu, Zhen Zou, and Gaolin Liang*. Spatially Quantitative Imaging of Enzyme Activity in a Living Cell J. Am. Chem. Soc. 2024. (DOI: 10.1021/jacs.4c14190).
200. Yu Deng,# Kui Yan,# Lingling Xu,# Xiaoyang Liu, Furong Zhao, Shangfeng Wang, Fan Zhang*, Gaolin Liang*, and Rui Wang*. “Turn-on” NIR-II fluorescence of a dually quenched probe for sensitive imaging of cathepsin B in vivo         Chem. Commun. 2025. (DOI: 10.1039/D4CC05784H).
199. Xiaofeng Wu, Yu Deng, Rui Wang, Heejeong Kim, Gyoungmi Kim, Ying Xu, Kyung Tae Hong, Jun-Seok Lee, Jing-Jing Hu*, Gaolin Liang*, and Juyoung Yoon*. Rational Design of an Activatable Near-Infrared Fluorogenic Platform for In Vivo Orthotopic Tumor Imaging and Resection Angew. Chem. Int. Ed. 2024, e202416877. (DOI: 10.1002/anie.202416877).
198. Runqun Tang, Ziyi Zhang, Xiaoyang Liu, Liangxi Zhu, Yuting Xu, Renjie Chai, Wenjun Zhan, Shurong Shen*, and Gaolin Liang*.  Fibroblast Growth Factor Receptor 1-Specific Dehydrogelation to Release Its Inhibitor for Enhanced Lung Tumor Therapy ACS Nano 2024, 18, 42, 29223–29232 (DOI: 10.1021/acsnano.4c11548).
197. Ziyi Zhang,# Runqun Tang,# Xiaoyang Liu, Xianbao Sun*, and Gaolin Liang*. Recent Advances in Self-Assembling Peptide-Based Nanomaterials for Enhanced
Photodynamic Therapy Macromol. Biosci. 2024, 202400409. (DOI: 10.1002/mabi.202400409).
196. Zihan Yuan,# Qiaochu Jiang,# and Gaolin Liang*. Inspired by nature: Bioluminescent systems for bioimaging applications. Talanta 2025, 281, 126821.  (DOI: 10.1016/j.talanta.2024.126821).
195. Xiaofeng Wu, Yu Deng, Ying Xu, Heemin Kang*, Jing-Jing Hu*, Juyoung Yoon*, and Gaolin Liang*. Activatable Fluorescence and Bio/Chemiluminescence Probes for Aminopeptidases: From Design to Biomedical Applications. Adv. Mater. 2024, 202409893.  (DOI: 10.1002/adma.202409893).
194. Yu Deng,# Lingling Xu,# Xiaoyang Liu, Qiaochu Jiang, Xianbao Sun, Wenjun Zhan*, and Gaolin Liang*. Tandem Targeting and Dual Aggregation of an AIEgen for Enhanced Near-Infrared Fluorescence Imaging of Tumors. J. Am. Chem. Soc. 2024, 146, 37, 25462–25466  (DOI: 10.1021/jacs.4c10606).
193. Xiaoyang Liu,# Qiaochu Jiang,# Yun Yin, and Gaolin Liang*. Phe–Phe-Based Macroscopic Supramolecular Hydrogel Construction Strategies and Biomedical Applications. Chem Bio Eng. 2024.  (DOI: 10.1021/cbe.4c00110).
192. Yun Yin,# Xiaoyang Liu,# Xuemei Li* and Gaolin Liang*. Click reaction-induced in situ nanoparticle aggregation for cancer imaging and treatment. EngMedicine 2024, 1, 100023.  (DOI: 10.1016/j.engmed.2024.100023).
191. Lingling Xu, Yu Deng, Hang Gao,  Yuchen Yao, Xiaoyang Liu, Wenjun Zhan, Gaolin Liang*, and  Xianbao Sun*. Near-infrared AIEgen for sulfatase imaging in breast cancer in vivoNanoscale 2024, 16, 11538-11541.  (DOI: 10.1039/D4NR01314J).
190. Han Yin, Yue Hua, Songwei Feng, Yi Xu, Yue Ding, Sicong Liu, Dongsheng Chen, Furong Du, Gaolin Liang*, Wenjun Zhan*, and Yang Shen*. In situ Nanofiber Formation Blocks AXL and GAS6 Binding to Suppress Ovarian Cancer Development. Adv. Mater. 2024, 36, 2308504.  (DOI: 10.1002/adma.202308504).
189. Lingling Xu,# Hang Gao,#  Yu Deng, Xiaoyang Liu, Wenjun Zhan, Xianbao Sun, Jing-Juan Xu, and Gaolin Liang*. β-Galactosidase-Activated near-infrared AIEgen for ovarian cancer imaging in vivoBiosens. Bioelectron.  2024, 255, 116207.  (DOI: 10.1016/j.bios.2024.116207 ).
188. Yanyan Zhou,# Lingling Xu,# Xianbao Sun, Wenjun Zhan,* and Gaolin Liang*In situ peptide assemblies for bacterial infection imaging and treatment. Nanoscale 2024, 16, 3211-3225.  (DOI: 10.1039/D3NR05557D).
187. Yang Yang,# Xiaoyang Liu,# Xiaofeng Wu,* and Gaolin Liang*. Enzyme-Instructed CBT-Cys-like Click Cyclization Reactions for Bioimaging. Chem. Biomed. Imaging. 2024, 2, 98-116.  (DOI: 10.1021/cbmi.3c00117).
2023
186. Lingling Xu,# Hang Gao,# Wenjun Zhan,# Yu Deng, Xiaoyang Liu, Qiaochu Jiang, Xianbao Sun, Jing-Juan Xu, and Gaolin Liang*. Dual Aggregations of a Near-Infrared Aggregation-Induced Emission Luminogen for Enhanced Imaging of Alzheimer's Disease. J. Am. Chem. Soc. 2023.  (DOI: 10.1021/jacs.3c10255).
185. Hongzhe Yan,# Xiaoyang Liu,# Caifeng Ding,* and Gaolin Liang*. Enzyme-Instructed Host-Guest Assembly/Disassembly for Biomedical Applications. ChemBioChem 2023, e202300648.  (DOI: 10.1002/cbic.202300648).
184. Xianbao Sun, Lingling Xu, Hai-Dong Xu, Limin Xie,Rui Wang, Zhimou Yang, Wenjun Zhan, Shurong Shen,* and Gaolin Liang*. Intracellular Nitroreductase-Triggered “On” and “Enhanced” Photoacoustic Signals for Sensitive Imaging of Tumor Hypoxia. Adv. Healthcare Mater. 2023. (DOI: 10.1002/adhm.202303472).
183. Guangqiong Xu, Qiao Weng, Lei Zhang, Yaye Song, Wenjun Zhan, Yuan Yin,  Gaolin Liang*, and Fuqiang Wang. Aurora Kinase B-Instruct Release of AZD1152-HQPA from Hydrogel to Enhance Cervical Cancer Suppression. Adv. Funct. Mater. 2023, 202309984. (DOI: 10.1002/adfm.202309984).
182. Xiaotong Cheng,# Tiantian Xia,# Xianbao Sun, Guowei Liang, Xiaoyang Liu, and Gaolin Liang*. Atg4B and Cathepsin B-Triggered in Situ Luciferin Formation for Precise Cancer Autophagy Bioluminescence Imaging. ACS Cent. Sci. 2023. (DOI: 10.1021/acscentsci.3c00696).
181. Xiaoyang Liu, Ya-Xuan Zhu, Hao-Ran Jia, Xinping Zhang, Ge Gao, Ke-Fei Xu, Xin-Wang Yu, Shi-Hao Wang, Zi-Xi Wang, Penghao Zhen, and Gaolin Liang*, and Fu-Gen Wu*. A MOF-based nanobomb for tumor microvascular occlusion and combined tumor starvation therapy and chemotherapy. Mater. Today nano 2023, 100430. (DOI: 10.1016/j.mtnano.2023.100430).
180. Xianbao Sun, Lingling Xu, Xiaoyang Liu, Hai-Dong Xu, Wenjun Zhan, and Gaolin Liang*. Activatable small molecular luminescence probes for autofluorescence-free bioimaging. Trends Anal. Chem. 2023. (DOI: 10.1016/j.trac.2023.117326).
179. Xinyi Hu, Xianbao Sun, Xiaoyang Liu, Hai-Dong Xu, Liang Yang, Songqin Liu, Rui Wang*, and Gaolin Liang*. Enhanced Photoacoustic Imaging of Urokinase-Type Plasminogen Activator Activity in Tumors. Anal. Chem. 2023, 95(39), 14511-14515. (DOI: 10.1021/acs.analchem.3c03305).
178. Liang Yang, Xianbao Sun, Lingling Xu, Xiaotong Cheng, Xiaoyang Liu, Yu Deng, Xinyi Hu, and Gaolin Liang*. β-Glucuronidase-Activated Bioluminescence Probe for In Vivo Tumor Imaging. Anal. Chem. 2023, 95(38), 14165-14168. (DOI: 10.1021/acs.analchem.3c03162).
177. Yanpeng Jia, Yi Zhang, Wenjun Zhan, Yu Wang, Xianbao Sun, Yuan Zhang, Xiaoyang Liu, Bing Han, Ying Bai, Ling Shen, Gaolin Liang*, Honghong Yao*. Release of Neuroprotective Drugs Curcumin andEdaravone from Supramolecular Hydrogel for IschemicStroke Treatment. Adv. Funct. Mater. 2023, 2303930. (DOI: 10.1002/adfm.202303930).
176. Xianbao Sun, Manli Wang, Xiaoyang Liu, Wenjun Zhan, Guangqiong Xu, Qiaochu Jiang, Hai-Dong Xu, Fuqiang Wang,* and Gaolin Liang*. Enzymatic self-assembly/disassembly turns “ON”/“OFF” the mimetic hydrolytic activity of histidine nanofibers. Sci. China Chem. 2023. (DOI: 10.1007/s11426-023-1788-5).
175. Ying Xu,# Qiaochu Jiang,# Xianbao Sun,* and Gaolin Liang*. Morphological Transformation of Self-Assembled Peptide Nanostructures for Bioimaging. Analysis & Sensing 2023, e20230003. (DOI: 10.1002/anse.202300039).
174. Hai-Dong Xu,# Xiaotong Cheng,# Xianbao Sun, Peiyao Chen, Wenjun Zhan, Xiaoyang Liu, Xinliang Wang, Bing Hu, and Gaolin Liang*. Caspase-3-Triggered Intracellular Gadolinium Nanoparticle Formation for T1-Weighted Magnetic Resonance Imaging of Apoptosis In Vivo. Nano Lett. 2023, 13, 6178–6183. (DOI: 10.1021/acs.nanolett.3c01787).
173. Qiaochu Jiang,# Wenjun Zhan,# Xiaoyang Liu, Lin Bai, Manli Wang, Ying Xu, and Gaolin Liang*. Assembly drives regioselective azide-alkyne cycloaddition reaction. Nat. Commun. 2023, 14, 3935. (DOI:10.1038/s41467-023-39658-0).
172. Wenjun Zhan,# Lingling Xu,# Zhiyu Liu,# Xiaoyang Liu, Ge Gao, Tiantian Xia, Xiaotong Cheng, Xianbao Sun, Fu-Gen Wu, Qian Yu, and Gaolin Liang*. Tandem Guest-Host-Receptor Recognitions Precisely Guide Ciprofloxacin to Eliminate Intracellular Staphylococcus aureus. Angew. Chem., Int. Ed. 2023, 62, e202306427. (DOI:10.1002/anie.202306427).
171. Yu Deng,# Xiang Shi,# Xinyi Hu,# Lingling Xu, Xiaoyang Liu, Ge Gao, Rui Wang*, and Gaolin Liang*. A Chemiluminescent Probe for Imaging Peroxynitrite in Inflammatory Cells and Tissues.Anal. Chem. 2023, 95(16), 6490-6500. (DOI:10.1021/acs.analchem.3c01124).
170. Xiaoyang Liu, Wenjun Zhan, Ge Gao, Qiaochu Jiang, Xinping Zhang, Hongbo Zhang, Xianbao Sun, Wei Han, Fu-Gen Wu, and Gaolin Liang*. Apoptosis-Amplified Assembly of Porphyrin Nanofiber Enhances Photodynamic Therapy of Oral Tumor. J. Am. Chem. Soc. 2023, 145(14), 7918-7930. (DOI:10.1021/jacs.2c13189).
169. Xianbao Sun, Tiantian Xia, Lingling Xu, Wenjun Zhan, and Gaolin Liang*. Facile Label-Free Three-Input Molecular Keypad Lock. Anal. Chem. 2023. (DOI: 10.1021/acs.analchem.3c00412).
168. Xinyi Hu,# Runqun Tang,# Lin Bai, Songqin Liu, and Gaolin Liang* and Xiaobao Sun*. CBT-Cys click reaction for optical bioimaging in vivo. VIEW 2023, 20220065. (DOI: 10.1002/VIW.20220065).
167. Wenjun Zhan, Ge Gao, Zhiyu Liu, Xiaoyang Liu, Lingling Xu, Manli Wang, Hai-Dong Xu, Runqun Tang, Jingyuan Cao, Xianbao Sun, and Gaolin Liang*.  Self-Assembly of Adamantane-Peptide Conjugate for Combating Staphylococcus aureus Infection. Adv. Healthcare Mater. 2023, 202203283. (DOI: 10.1002/adhm.202203283).
2022
166. Haidong Xu, Rui Wang*, and Gaolin Liang*. Applications of Self-assembled Peptide Probes in Magnetic Resonance Imaging. Chem. J. Chinese Universities 2022, 43(12), 20220440. (DOI:10.7503/cjcu20220440).
165.Lingling Xu,# Nanhui Liu,# Wenjun Zhan,# Yu Deng, Zhaoxia Chen, Xiaoyang Liu, Ge Gao, Qian Chen, Zhuang Liu, and Gaolin Liang*. Granzyme B Turns Nanoparticle Fluorescence “On” for Imaging Cytotoxic T Lymphocyte Activity in Vivo. ACS Nano 2022, 16(11), 1932819334.  (DOI:10.1021/acsnano.2c08896).
164.Yaguang Wang, Di Wang, Chao Wu, Bin Wang, Shufang He, Hua Wang, Gaolin Liang*, and Ye Zhang*. MMP 9-instructed assembly of bFGF nanofibers in ischemic myocardium to promote heart repair. Theranostics 2022, 12(17), 72377249. (DOI:10.7150/thno.77345).
163.Xiaotong Cheng, Tiantian Xia, Wenjun Zhan, Hai-Dong Xu, Jiaoming Jiang, Xiaoyang Liu, Xianbao Sun, Fu-Gen Wu, and Gaolin Liang*. Enzymatic Nanosphere-to-Nanofiber Transition and Autophagy Inducer Release Promote Tumor Chemotherapy. Adv. Healthcare Mater. 2022,11, 2201916. (DOI: 10.1002/adhm.202201916).
162.Tiantian Xia,# Xiaotong Cheng,# Xianbao Sun*, and  Gaolin Liang*. Photoswitchable Nanofiber–Nanoparticle Transformation in a Cosolvent Gel–Sol System. ACS Materials Lett. 2022, 4(10), 1962–1966. (DOI: 10.1021/acsmaterialslett.2c00670).
161.Ge Gao, Xianbao Sun, Xiaoyang Liu, Runqun Tang, Manli Wang, Wenjun Zhan, Junnian Zheng*, and  Gaolin Liang*. FAP-α-Instructed Coumarin Excimer Formation for High Contrast Fluorescence Imaging of Tumor. Nano Lett. 2022, 22(16), 6782–6786. (DOI: 10.1021/acs.nanolett.2c02540).
160. Ge Gao,# Yao-Wen Jiang,# Wenjun Zhan, Xiaoyang Liu, Runqun Tang, Xianbao Sun, Yu Deng, Lingling Xu, and Gaolin Liang*. A Trident Molecule with Nanobrush-Nanoparticle-Nanofiber Transition Property Spatially Suppresses Tumor Metastasis. J. Am. Chem. Soc. 2022, 144(26), 11897–11910. (DOI: 10.1021/jacs.2c05743).
159. Sicheng Liang, Zhuang Wang, Zhixin Zhou, Gaolin Liang*, Yuanjian Zhang*. Polymeric carbon nitride-based materials: Rising stars in bioimaging. Biosens. Bioelectron. 2022, 211, 114370. (DOI: 10.1016/j.bios.2022.114370).
158. Xiang Shi,# Ge Gao,# Xiaoyang Liu, Lingling Xu, Yu Deng, Rui Wang*, Gaolin Liang*. Highly lipophilic coumarin fluorophore with excimer-monomer transition property for lipid droplet imaging. Chin. Chem. Lett. 2023, 34, 107613. (DOI: 10.1016/j.cclet.2022.06.036).
157. Yue Hua, Han Yin, Xiaoyang Liu, Jinbing Xie, Wenjun Zhan*, Gaolin Liang* and Yang Shen*. Salt-inducible Kinase 2-Triggered Release of Its Inhibitor from Hydrogel to Suppress Ovarian Cancer Metastasis. Adv. Sci. 2022, 2202260. (DOI: 10.1002/advs.202202260).
156. Lingling Xu, Wenjun Zhan, Yu Deng, Xiaoyang Liu, Ge Gao, Xianbao Sun, and Gaolin Liang*. ROS Turn Nanoparticle Fluorescence on for Imaging Staphylococcus aureus Infection in Vivo. Adv. Healthcare Mater. 2022, 208, 2200453. (DOI: 10.1002/adhm.202200453).
155. Xiang Shi,# Yu Deng,# Xiaoyang Liu, Ge Gao, Rui Wang, and Gaolin Liang*. An aminopeptidase N-activatable chemiluminescence probe for image-guided surgery and metastasis tracking of tumor. Biosens. Bioelectron. 2022, 208, 114-212. (DOI: 10.1016/j.bios.2022.114212).
154. Bin Wang,# Chengfan Wu,# Shufang He, # Yaguang Wang, Di Wang, Hui Tao, Chenchen Wang, Xiaoxi Pang, Fei Li, Yue Yuan, Eric R. Gross, Gaolin Liang,* and Ye Zhang*. V1-Cal hydrogelation enhances its effects on ventricular remodeling reduction and cardiac function improvement post myocardial infarction. Chem. Eng. J. 2022, 433, 134450. (DOI: 10.1016/j.cej.2021.134450).
153. Rui Luo, Chunqing Ou, Xinchao Li, Yanfang Wang, Wei Du, Gaolin Liang,* and Changyang Gong*. An Acidity-Initiated Self-Assembly/Disassembly Nanoprobe to Switch on Fluorescence for Tumor Targeted Near-Infrared Imaging. Nano Lett. 2022, 22, 151156. (DOI: 10.1021/acs.nanolett.1c03534).
152. Chenchen Wang, Wei Du, Chengfan Wu, Shan Dan, Miao Sun, Tong Zhang, Bin Wang, Yue Yuan,* and Gaolin Liang*.  Cathespin B-Initiated Cypate Nanoparticle Formation for Tumor Photoacoustic Imaging. Angew. Chem., Int. Ed. 2022, 61, e202114766. (DOI: 10.1002/anie.202114766).

151. Huan Li,# Zijuan Hai,# Liwei Zou, Lele Zhang, Lulu Wang, Longsheng Wang,* and Gaolin Liang*. Simultaneous enhancement of T1 and T2 magnetic resonance imaging of liver tumor at respective low and high magnetic fields. Theranostics 2022, 12(1), 410-417. (DOI: 10.7150/thno.67155).
2021
150. Chengfan Wu, Chenchen Wang, Tong Zhang, Mengxing Wei, Yinglu Chen, Xiaoyan Li, Fuqiang Wang,* and Gaolin Liang*. Lysosome-Targeted and Fluorescence-Turned “On” Cytotoxicity Induced by Alkaline Phosphatase-Triggered Self-Assembly. Adv. Healthcare Mater. 2021, 11, 2101346. (DOI: 10.1002/adhm.202101346).
149. Xiaodong Zhang, Xiaokai Chen,Yuxin Guo,Ge Gao, Dongdong Wang, Yinglong Wu, Jiawei Liu, Gaolin Liang, Yanli Zhao,* Fu-Gen Wu*. Dual Gate-Controlled Therapeutics for Overcoming Bacterium-Induced Drug Resistance and Potentiating Cancer Immunotherapy. Angew. Chem., Int. Ed. 2021, 60, 14013-14021. (DOI: 10.1002/anie.202102059).
148, Tiantian Xia,# Xiaotong Cheng,# Wenjun Zhan,* Gaolin Liang*. Luciferase-Luciferin Bioluminescence System for Bioimaging Applications. Analysis & Sensing. 2021, 1, 138-147. (DOI: 10.1002/anse.202100035).
147, Qiaochu Jiang,# Xiaoyang Liu,# Gaolin Liang,* and Xianbao Sun*. Self-assembly of peptide nanofibers for imaging applications. Nanoscale 2021, 13, 15142-15150.(DOI: 10.1039/D1NR04992E).
146, Zhiyu Liu, Wenjun Zhan,* and Gaolin Liang*. In Situ Activatable Peptide-based Nanoprobes for Tumor Imaging. Chem. Res. Chinese Universities 2021, 37(4), 889-899. (DOI: 10.1007/s40242-021-1181-8).
145, Yinglu Chen, Chengfan Wu, Chenchen Wang, Tong Zhang, Yue Hua, Yang Shen,* and Gaolin Liang*. Bioluminescence Imaging of Urokinase-Type Plasminogen Activator Activity in Vitro and in Tumors. Anal. Chem. 2021, 93(29), 9970-9973. (DOI: 10.1021/acs.analchem.1c02499).
144, Ge Gao,# Xianbao Sun,# Xiaoyang Liu, Yao-Wen Jiang, Xiaotong Cheng, Runqun Tang, Yuxin Guo,  Fu-Gen Wu* and Gaolin Liang*. Intracellular Nanoparticle Formation and Hydroxychloroquine Release for Autophagy-Inhibited Mild-Temperature Photothermal Therapy for Tumors. Adv. Funct. Mater. 2021, 2102832. (DOI: 10.1002/adfm.202100738).
143,  Xiaotong Cheng, Hai-Dong Xu, Huan-Huan Ran, Fu-Gen Wu,* and Gaolin liang*. Glutathione-Depleting Nanomedicines for Synergistic Cancer Therapy. ACS Nano 2021, 15(5), 8039–8068. (DOI:10.1021/acsnano.1c00498).
142, Ge Gao, Xianbao Sun,* and Gaolin liang*. Nanoagent-Promoted Mild-T emperature Photothermal Therapy for Cancer Treatment. Adv. Funct. Mater., 2021, 2100738. (DOI: 10.1002/adfm.202100738).
141, Peiyao Chen, Hongyong Wang, Hao Wu, Pei Zou, Chenchen Wang, Xiaoyang Liu, Yue Pan, Yaling Liu, and Gaolin liang*. Intracellular Synthesis of Hybrid Gallium-68 Nanoparticle Enhances MicroPET Tumor Imaging. Anal. Chem. 2021, 6329-6334. (DOI: 10.1021/acs.analchem.1c00747).
140, Miaomiao Zhang, Chenchen Wang, Chen Yang, Haisi Wu, Huae Xu*, and Gaolin liang*. Using Fluorescence On/Off to Trace Tandem Nanofiber Assembly/Disassembly in Living Cells. Anal. Chem. 2021, 93, 14, 5665-5669. (DOI: 10.1021/acs.analchem.1c00220).
2020
139, Renuka Khatik, Zhengyun Wang, Fenfen Li, Debo Zhi,Sonia Kiran, Pankaj Dwivedi, Ronald X. Xu, Gaolin Liang*, Bensheng Qiu*, Qing Yang*. Magnus nano-bullets” as T1/T2 based dual-modal for in vitro and in vivo MRI visualization. Nanomedicine 2019, 15, 264-273 (DOI: 10.1016/j.nano.2018.10.005).
138, Xiao Hu, Zijuan Hai, Chengfan Wu, Wenjun Zhan,  and Gaolin Liang*. A Golgi-Targeting and Dual-Color “Turn-On” Probe for Spatially Precise Imaging of Furin. Anal. Chem. 2021, 93, 3, 1636-1642 (DOI: 10.1021/acs.analchem.0c04186).
137, Zhonghua Shi*, Xiaoyan Li, Mengxing Wei, Peiyao Chen, Ting Zhang, Xiufeng Ling, Junqiang Zhang, Chun Zhao*, Fuqiang Wang*, and  Gaolin Liang*. Receptor tyrosine kinases-instructed release of its inhibitor from hydrogel to delay ovarian aging. Biomaterials 2020, 120536. (DOI: 10.1016/j.biomaterials.2020.120536).
136, Chenchen Wang, Wei Du, Tong Zhang, and  Gaolin Liang*.A Bioluminescent Probe for Simultaneously Imaging Esterase and Histone Deacetylase Activity in a Tumor. Anal. Chem. 2020, 15275-15279. (DOI: 10.1021/acs.analchem.0c04227).
135, Miaomiao Zhang, Yong Guan, Zheng Dang, Pinggen Zhang, Zhen Zheng, Liang Chen, Wen Kuang, Chenchen Wang, Gaolin Liang*.Directly observing intracellular nanoparticle formation with nanocomputed tomography. Sci. Adv. 2020, 6, eaba3190 (DOI: 10.1126/sciadv.aba3190).
134, Jihua Chen, Yinchu Ma, Wei Du, Tianyue Dai, Yanfang Wang, Wei Jiang, Yifei Wan, Yucai Wang, Gaolin Liang* and Guangfeng Wang*. Furin-Instructed Intracellular Gold Nanoparticle Aggregation for Tumor Photothermal Therapy. Adv. Funct. Mater. 2020, 2001566 (DOI: 10.1002/adfm.202001566).
133, Meihui Zhuang, Zhuanghao Hou, Peiyao Chen, Gaolin Liang* and Guangming Huang*. Introducing charge tag via click reaction in living cells for single cell mass spectrometry. Chem.Sci. 2020, 11, 7308 (DOI: 10.1039/d0sc00259c).
132, Mengya Lv, Yanhao Zhang, Jiayi Fan, Yanyun Yang, Sheng Chen*, Gaolin Liang*, and Shusheng Zhang*. A near-infrared fluorescent probe for ratiometric sensing of SO2 in cells and zebrafish. Analyst 2020, Advance Article (DOI: 10.1039/d0an01468k).
131, Yaguang Wang, Xiaohu Li, Peiyao Chen, Yu Dong, Gaolin Liang* and Yongqiang Yu*. Enzyme-instructed self-aggregation of Fe3O4 nanoparticles for enhanced MRI T2 imaging and photothermal therapy of tumors. Nanoscale 2020, 12, 1886 (DOI: 10.1039/c9nr09235h).
130, Xiaoyang Liu, Xianbao Sun* and Gaolin liang*. Peptide-based supramolecular hydrogels for bioimaging applications. Biomater. Sci. 2020 (DOI: 10.1039/d0bm01020k).
129, Yu Deng, Wenjun Zhan* and Gaolin liang*. Intracellular Self-Assembly of Peptide Conjugates for Tumor Imaging and Therapy. Adv. Healthcare Mater. 2020, 2001211 (DOI: 10.1002/adhm.202001211).
128, Yanfang Wang, Wei Du, Tong Zhang, Yu Zhu, Yanhan Ni, Chenchen Wang, Fatima Maria Sierra Raya, Liwei Zou, Longsheng Wang,* and Gaolin Liang*. A Self-Evaluating Photothermal Therapeutic
Nanoparticle. ACS Nano 2020, 14, 9585-9593 (DOI: 10.1021/acsnano.9b10144).
127, Ge Gao, Yaowen Jiang, Yuxin Guo, Haoran Jia, Xiaotong Cheng, Yu Deng, Xinwang Yu, Yaxuan Zhu, Haoyue Guo, Wei Sun, Xiaoyang Liu, Jing Zhao, Shihe Yang, Zhiwu Yu, Fatima Maria Sierra Raya, Gaolin Liang* and Fugen Wu*. Enzyme-Mediated T umor Starvation and Phototherapy Enhance Mild-T emperature Photothermal Therapy. Adv. Funct. Mater. 2020, 30, 1909391 (DOI: 10.1002/adfm.201909391)
126, Xiaotong Cheng, Jiaoming Jiang and Gaolin Liang*. Covalently Conjugated Hydrogelators for Imaging and Therapeutic Applications.Bioconjugate Chem. 2020, 30, 1909391 (DOI: 10.1002/adfm.201909391)
2019
125, Yanhan Ni, Zijuan Hai, Tong Zhang, Yanfang Wang, Yanyun Yang, Shusheng Zhang*, and Gaolin Liang*. Cathepsin B Turning Bioluminescence “On” for Tumor Imaging. Anal. Chem. 2019, 91, 23, 14834-14837 (DOI: 10.1021/acs.analchem.9b04254).

124, Hongyong Wang, Peiyao Chen, Hao Wu, Pei Zou, Jun Wu, Yaling Liu*, and Gaolin Liang*. Furin-Guided Intracellular 68Ga Nanoparticle Formation Enhancing Tumor MicroPET Imaging. Anal. Chem. 2019, 91, 23, 14842-14845 (DOI: 10.1021/acs.analchem.9b04788).
123, Wei Du, Yuanyuan Chong, Xiaomu Hu, Yanfang Wang, Yu Zhu, Jihua Chen, Xiaoxia Li, Qun Zhang, Guangfeng Wang,* Jun Jiang,* and Gaolin Liang*. Increasing Photothermal Efficacy by Simultaneous Intra- and Intermolecular Fluorescence Quenching. Adv. Funct. Mater. 2020, 30, 1908073 (DOI: 10.1002/adfm.201908073).
122, Peiyao Chen, Wen Kuang, Zhen Zheng, Shuye Yang, Yaling Liu, Lanhong Su, Kui Zhao,* and Gaolin Liang*.Carboxylesterase-Cleavable Biotinylated Nanoparticle for Tumor-Dual Targeted Imaging.Theranostics 2019, 9(24), 7359-7369 (DOI: 10.7150/thno.37625).
121, Zhanling Ding, Hongbin Sun, Shuchao Ge, Yuan Cai, Yue Yuan, Zijuan Hai, Tongxiang Tao, Jinming Hu,* Bing Hu,* Junfeng Wang,* and Gaolin Liang*. Furin-Controlled Fe3O4 Nanoparticle Aggregation and 19F Signal “Turn-On” for Precise MR Imaging of Tumor. Adv. Funct. Mater. 2019,1903860 (DOI: 10.1002/adfm.201903860).
120, Jiali Tan,* Mei Zhang, Zijuan Hai, Chengfan Wu, Jiong Lin, Wen Kuang, Hang Tang, Yulei Huang, Xiaodan Chen, and Gaolin Liang*. Sustained Release of Two Bioactive Factors from Supramolecular Hydrogel Promotes Periodontal Bone Regeneration. ACS Nano 2019, 13(5), 5616-5622(DOI: 10.1021/acsnano.9b00788).
119, Zijuan Hai, Yanhan Ni, Dilizhatai Saimi, Hongyi Yang, Haiyang Tong, Kai Zhong,* and Gaolin Liang*. γ-Glutamyltranspeptidase-Triggered Intracellular Gadolinium Nanoparticle Formation Enhances the T2-Weighted MR Contrast of Tumor. Nano Lett. 2019, 19(4), 2428-2433, (DOI: 10.1021/acs.nanolett.8b05154).
118, Peiyao Chen,# Yinchu Ma,# Zhen Zheng,# Chengfan Wu, Yucai Wang,* and Gaolin Liang*. Facile syntheses of conjugated polymers for photothermal tumour therapy. Nat. Commun. 2019, 2019, 10, 1192 (DOI: 10.1038/s41467-019-09226-6).
2018
117, Chengfan Wu, Rui Zhang, Wei Du, Liang Cheng,* and Gaolin Liang*. Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors. Nano Lett. 2018, 18(12), 7749-7754(DOI: 10.1021/acs.nanolett.8b03482).
116, Wei Tang, Zhibin Zhao, Yuanyuan Chong, Chengfan Wu, Qingzhi Liu, Jingbo Yang, Rongbin Zhou, Zhe-Xiong Lian,* and Gaolin Liang*. Tandem Enzymatic Self-Assembly and Slow Release of Dexamethasone Enhances Its Antihepatic Fibrosis Effect. ACS Nano 2018, 12(10), 9966-9973(DOI: 10.1021/acsnano.8b04143).
115, Jindao Wu,* Zhen Zheng, Yuanyuan Chong, Xiangcheng Li, Liyong Pu, Qiyun Tang, Liu Yang, Xuehao Wang,* Fuqiang Wang,*, and Gaolin Liang*. Immune Responsive Release of Tacrolimus to Overcome Organ Transplant Rejection. Adv. Mater. 2018, 30(45), 1805018 (DOI: 10.1002/adma.201805018).Video Abstract:  https://v.qq.com/x/page/l0788apvupo.html.
114, Yue Zhao, Zijuan Hai, Hongyong Wang, Lanhong Su, and Gaolin Liang*. Legumain-Specific Near-Infrared Fluorescence “Turn On” for Tumor-Targeted Imaging. Anal. Chem. 2018,  90(15), 8732-8735 (DOI: 10.1021/acs.analchem.8b02704).
113, Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng*, Wei Jiang*, and Rongbin Zhou*. Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity. Nat. Commun. 2018, 9, 2550 (DOI: 10.1038/s41467-018-04947-6).
112, Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,* and Rongbin Zhou*. Tranilast directly targets NLRP3 to treat inflammasome-driven diseases. EMBO Mol. Med. 2018, 10: e8689 (DOI: 10.15252/emmm.201708689).
111, Miaomiao Zhang and Gaolin Liang*. Applications of CBT-Cys click reaction: past, present, and future. Sci. China Chem. 2018, 61(9), 1088-1098 (DOI: 10.1007/s11426-018-9277-6).
110, Zijuan Hai and Gaolin Liang*. Intracellular Self-Assembly of Nanoprobes for Molecular Imaging. Adv. Biosys. 2018, 2(8), 1800108 (DOI: 10.1002/adbi.201800108).
109, Miaomiao Zhang, Lin Wang, Yangyang Zhao, Fuqiang Wang, Jindao Wu*, and Gaolin Liang*. Using Bioluminescence Turn-On to Detect Cysteine in Vitro and in Vivo. Anal. Chem. 2018, 90(8), 4951-4954 (DOI: 10.1021/acs.analchem.8b00682).
108, Jindan Li, Zijuan Hai, Huiqiong Xiao, Xiaoyi Yi*, and Gaolin Liang*. Intracellular self-assembly of Ru(bpy)32+ nanoparticles enables persistent phosphorescence imaging of tumor. Chem. Commun. 2018, 54, 3460-3463 (DOI: 10.1039/C8CC01759J)
107, Sonia Kiran, Zijuan Hai, Zhanling Ding, Lin Wang, Yaling Liu, Huafeng Zhang, and Gaolin Liang*. Alkaline phosphatase-triggered assembly of etoposide enhances its anticancer effect. Chem. Commun. 2018, 54, 1853-1856 (DOI: 10.1039/C7CC09365A).
106, Zijuan Hai, Jingjing Wu, Dilizhatai Saimi, Yanhan Ni, Rongbin Zhou, and Gaolin Liang*. Smart Dual Quenching Strategy Enhances the Detection Sensitivity of Intracellular Furin. Anal. Chem. 2018, 90(3), 1520-1524 (DOI: 10.1021/ acs.analchem.7b05251).
105, Wei Du, Xiaomu Hu, Weichen Wei, and Gaolin Liang*. Intracellular Peptide Self-Assembly: A Biomimetic Approach for in Situ Nano-drug Preparation. Bioconjugate Chem. 2018, 29(4), 826-837 (DOI: 10.1021/ acs.bioconjchem.7b00798).
104: Wei Tang,# Zhibin Zhao,# Zhexiong Lian, and Gaolin Liang*. Fluorogenic Disassembly of Self-Quenched NIR Nanoparticles Enables Matrix Metalloproteinase Detection. J. Biomed. Nanotechnol. 2018, 14, 304-311 (DOI: 10.1166/ jbn.2017.2473).
2017
103: Wei Tang, Jingbo Yang, Zhibin Zhao, Zhexiong Lian and Gaolin Liang*. Intracellular coassembly boosts the anti-inflammation capacity of dexamethasone. Nanoscale, 2017, 9, 17717-17721 (DOI:10.1039/C7NR07197C).
102: Jinhui Jiang, Zhibin Zhao, Zijuan Hai, Hongyong Wang, and Gaolin Liang*. Intracellular Proteolytic Disassembly of Self-Quenched NIR Nanoparticles Turns Fluorescence on for Tumor-Targeted Imaging. Anal. Chem. 2017, 89(18), 9625-9628 (DOI: 10.1021/ acs.analchem.7b02971).
101: Chengfan Wu,# Zhen Zheng,# Yuenan Guo, Chongli Tian, Qiang Xue,* and Gaolin Liang*.  Fluorine substitution enhances the self-assembling ability of hydrogelators. Nanoscale  2017, 9, 11429-11433 (DOI: 10.1039/C7NR02499A). #, equal contribution.
100: Ling Dong, Junchao Qian, Zijuan Hai, Jinyong Xu, Wei Du, Kai Zhong,* and Gaolin Liang*. Alkaline Phosphatase-Instructed Self-Assembly of Gadolinium Nanofibers for Enhanced T2-Weighted Magnetic Resonance Imaging of Tumor. Anal. Chem. 2017, 89(13), 6922-6925 (DOI: 10.1021/ acs.analchem.7b00621).
99: Zijuan Hai, Jingjing Wu, Lin Wang, Jiacheng Xu, Huafeng Zhang, and Gaolin Liang*. Bioluminescence Sensing of γ-Glutamyltranspeptidase Activity in Vitro and in Vivo. Anal. Chem. 2017, 89(13), 7017-7021 (DOI: 10.1021/ acs.analchem.7b00567).
98: Peiyao Chen, Zhen Zheng, Yunxia Zhu, Yu Dong, Fuqiang Wang,* and Gaolin Liang*. Bioluminescent Turn-On Probe for Sensing Hypochlorite in Vitro and in Tumors. Anal. Chem. 2017, 89(11), 5693-5696 (DOI: 10.1021/ acs.analchem.7b01103).
97: Wei Tang,# Jingbo Yang,# Yue Yuan,  Zhibin Zhao, Zhexiong Lian* and Gaolin Liang*.  Paclitaxel nanoparticle awakens immune system to fight against cancer. Nanoscale  2017, 9, 6529-6536 (DOI: 10.1039/C6NR09895A). #, equal contribution
96: Zhen Zheng, Gongyu Li, Chengfan Wu, Miaomiao Zhang, Yue Zhao, and Gaolin Liang*.  Intracellular synthesis of D-aminoluciferin for bioluminescence generation. Chem. Commun.  2017, 53, 3567-3570 (DOI: 10.1039/C7CC00999B).
95: Ning Zhou, Xiaoyan Cao, Xuewen Du, Huaimin Wang, Ming Wang, Shuang Liu, Khang Nguyen, Klaus Schmidt-Rohr, Qiaobing Xu, Gaolin Liang and Bing Xu*. Hyper-Crosslinkers Lead to Temperature- and pH-Responsive Polymeric Nanogels with Unusual Volume Change. Angew. Chem. Int. Ed.. 2017, 56(10), 2623-2627 (DOI: 10.1002/anie.201611479).
94: Zijuan Hai, Jindan Li, Jingjing Wu, Jiacheng Xu and Gaolin Liang*. Alkaline Phosphatase-Triggered Simultaneous Hydrogelation and Chemiluminescence. J. Am. Chem. Soc.  2017. 139(3), 1041-1044 (DOI: 10.1021/jacs.6b11041). (Open Access).
93: Xiaomei Liu and Gaolin Liang*. Dual aggregation-induced emission for enhanced fluorescence sensing of furin activity in vitro and in living cells. Chem. Commun.  2017, 53, 1037-40 (DOI: 10.1039/C6CC09106G). (Back Cover).
2016
92: Zhen Zheng,# Anming Tang,# Yong Guan, Liang Chen, Fuqiang Wang, Peiyao Chen, Weijuan Wang, Yufeng Luo, Yangchao Tian and Gaolin Liang*.  Nanocomputed Tomography Imaging of Bacterial Alkaline Phosphatase Activity with an Iodinated Hydrogelator. Anal. Chem. 2016, 88(24), 11982-85 (DOI: 10.1021/ acs.analchem.6b04139). #, co-first author.
91: Bin Mei and Gaolin Liang*. Paclitaxel Hydrogelator Delays Microtubule Aggregation. Chin. J. Chem. Phys.  2017, 30(2), 239-242. (DOI: 10.1063/1674-0068/30/cjcp1609179)
90: Zhen Zheng and Gaolin Liang*. Magnetic resonance imaging-guided stratified selection of patients for nano-therapy. Ann. Transl. Med. 2016, 4(Suppl 1), S54 (DOI: 10.21037/atm.2016.10.07).
89: Zhen Zheng, Peiyao Chen, Maolin Xie, Chengfan Wu, Yufeng Luo, Wentao Wang, Jun Jiang and Gaolin Liang*. Cell Environment-Differentiated Self-Assembly of Nanofibers. J. Am. Chem. Soc. 2016, 138(35), 11128-11131 (DOI: 10.1021/jacs.6b06903).
88: Zhen Zheng,# Peiyao Chen,# Gongyu Li,# Yunxia Zhu,# Zhonghua Shi, Yufeng Luo, Chun Zhao, Ziyi Fu,  Xianwei Cui, Chenbo Ji, Fuqiang Wang,* Guangming Huang,* and Gaolin Liang*. Mechanistic study of CBT-Cys click reaction and its application for identifying bioactive N-terminal cysteine peptides in amniotic fluid. Chem. Sci. 2017, 8, 214-222 (DOI: 10.1039/C6SC01461E). #, co-first author.
87: Zhen Zheng,# Jihao Wang,# Peiyao Chen, Maolin Xie, Lei Zhang, Yubin Hou, Xin Zhang, Jun Jiang, Junfeng Wang,* Qingyou Lu,* and Gaolin Liang*. Using L-STM to directly visualize enzymatic self-assembly/disassembly of nanofibers. Nanoscale 2016, 8, 15142-15146 (DOI: 10.1039/C6NR03056D). #, co-first author.
86: Yue Yuan,# Fuqiang Wang,# Wei Tang, Zhanling Ding, Lin Wang, Lili Liang, Zhen Zheng, Huafeng Zhang, and Gaolin Liang*. Intracellular Self-Assembly of Cyclic D-Luciferin Nanoparticles for Persistent Bioluminescence Imaging of Fatty Acid Amide Hydrolase. ACS Nano 2016, 10(7), 7147-7153 (DOI: 10.1021/acsnano.6b03412). #, co-first author.
85: Fenfen Li, Debo Zhi, Yufeng Luo, Jiqian Zhang, Xiang Nan, Yunjiao Zhang, Wei Zhou, Bensheng Qiu,* Longping Wen,* and Gaolin Liang*. Core/shell Fe3O4/Gd2O3 nanocubes as T1-T2 dual modal MRI contrast agents. Nanoscale 2016, 8, 12826-12833 (DOI: 10.1039/C6NR02620F).
84: Anming Tang,# Yu Qian,# Shuang Liu,# Weijuan Wang, Bing Xu, An Qin,* and Gaolin Liang*. Self-assembling bisphosphonates into nanofibers to enhance their inhibitory capacity on bone resorption. Nanoscale 2016, 8, 10570-10575 (DOI: 10.1039/C6NR00843G). #, co-first author.
83: Zhen Zheng, Lin Wang,  Wei Tang, Peiyao Chen, Hui Zhu, Yue Yuan, Gongyu Li, Huafeng Zhang, and Gaolin Liang*. Hydrazide D-luciferin for in vitro selective detection and intratumoral imaging of Cu2+. Biosens. Bioelectron. 2016, 83, 200-204 (DOI: 10.1016/j.bios.2016.04.067).
82: Yue Yuan,# Zhanling Ding,# Junchao Qian, Jia Zhang, Jinyong Xu, Xuejiao Dong, Tao Han, Shuchao Ge, Yufeng Luo, Yuwei Wang, Kai Zhong,* and Gaolin Liang*. Casp3/7-Instructed Intracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging of Tumor Apoptosis. Nano Lett. 2016, 16 (4), 2686-2691 (DOI: 10.1021/acs.nanolett.6b00331). #, co-first author
81: Xiaomei Liu, Shuang Liu, and Gaolin Liang*. Fluorescence turn-on for highly selective detection of nitric oxide in vitro and in living cells. Analyst 2016,141, 2600-2605 (DOI: 10.1039/C6AN00110F).
80: Zhen Zheng, Hongbin Sun, Chen Hu, Gongyu Li, Xiaomei Liu, Peiyao Chen, Yusi Cui, Jing Liu, Junfeng Wang, and Gaolin Liang*. Using “On/Off” 19F NMR/MRI Signals to Sense Tyrosine Kinase/Phosphatase Activity in Vitro and in Cell Lysates. Anal. Chem. 2016, 88(6), 3363-3368 (DOI: 10.1021/acs.analchem.6b00036).
79: Yusi Cui, Wei Du, and Gaolin Liang*. Self-Assembly/Disassembly of Nanostructures Confers “Off/On” Signal for Molecular Imaging. ChemNanoMat 2016, 2(5) 344-353 (DOI: 10.1002/cnma.201600052).
78: Shuang Liu, Yufeng Luo, and Gaolin Liang*. In situ clicking methylglyoxal for hierarchical self-assembly of nanotubes in supramolecular hydrogel. Nanoscale. 2016, 8, 766-769. (DOI: 10.1039/C5NR07179H).
2015
77: Wei Du, Yue Yuan, Lin Wang, Yusi Cui, Hui Wang, Huiqin Xu*, and Gaolin Liang*. Multifunctional Bioconjugate for Cancer Cell-Targeted Theranostics. Bioconjugate Chem., 2015,  26 (12), 2571-78. (DOI: 10.1021/acs.bioconjchem.5b00570).
76: Bin Mei,# Qingqing Miao,# Anming Tang, and Gaolin Liang*. Enzyme-instructed self-assembly of taxol promotes axonal branching. Nanoscale. 2015, 7, 15605-15608 (DOI: 10.1039/C5NR04563K). #: Co-first author.
75: Yue Yuan, Di Li, Jia Zhang, Xianmin Chen, Chi Zhang, Zhanling Ding, Lin Wang, Xueqian Zhang, Junhua Yuan, Yinmei Li, Yanbiao Kang, and Gaolin Liang*. Bridging cells of three colors with two bio-orthogonal click reactions. Chem. Sci.. 2015, 6, 6425-6431 (DOI: 10.1039/C5SC01315A).
74: Ling Dong, Qingqing Miao, Zijuan Hai, Yue Yuan, and Gaolin Liang*. Enzymatic Hydrogelation-Induced Fluorescence Turn-Off for Sensing Alkaline Phosphatase in Vitro and in Living Cells. Anal. Chem.. 2015, 87(13), 6475-6478 (DOI: 10.1021/acs.analchem.5b01657).
73: Yaling Liu,# Qingqing Miao,# Pei Zou, Longfei Liu, Xiaojing Wang, Linna An, Xiaoliu Zhang, Xiangping Qian, Shineng Luo,* and Gaolin Liang*. Enzyme-Controlled Intracellular Self-Assembly of 18F Nanoparticles for Enhanced MicroPET Imaging of Tumor. Theranostics. 2015, 5(10), 1058-1067 (DOI: 10.7150/thno.11758). #: Co-first author.
72: Qingqing Miao, Chunying Yin, Maolin Xie, Yufeng Luo, Zijuan Hai, Qingpan Yuan, Jun Jiang, and Gaolin Liang*. Gathering nanorings via Fe2+-bipyridine coordination. Chem. Commun.. 2015, 51, 11045-11047 (DOI: 10.1039/C5CC02694F).
71: Yue Yuan,# Lin Wang,# Wei Du, Zhanling Ding, Jia Zhang, Tao Han, Linna An, Huafeng Zhang*, and Gaolin Liang*. Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multi-Drug Resistance. Angew. Chem. Int. Ed.. 2015, 54, 9700-9704 (DOI: 10.1002/anie.201504329 and 10.1002/ange.201504329). #: Co-first author.
70: Yue Yuan, Jia Zhang, Qinjingwen Cao, Linna An, Gaolin Liang*. Intracellular Disassembly of Self-Quenched Nanoparticles Turns NIR Fluorescence on for Sensing Furin Activity in Cells and in Tumors. Anal. Chem.. 2015, 87(12), 6180-6185 (DOI: 10.1021/acs.analchem.5b01656).
69: Yue Yuan, Shuchao Ge, Hongbin Sun, Xuejiao Dong, Hongxin Zhao, Linna An, Jia Zhang, Junfeng Wang, Bing Hu, Gaolin Liang*. Intracellular Self-Assembly and Disassembly of 19F Nanoparticles Confer Respective “Off” and “On” 19F NMR/MRI Signals for Legumain Activity Detection in Zebrafish. ACS Nano. 2015, 9(5), 5117-5124 (DOI: 10.1021/acsnano.5b00287).
68: Qingqing Miao, Qing Li, Qingpan Yuan, Lingli Li, Zijuan Hai, Shuang Liu, and Gaolin Liang*. Discriminative Fluorescence Sensing of Biothiols in Vitro and in Living Cells. Anal. Chem.. 2015, 87 (6), 3460-3466 (DOI: 10. 1021/ac504836a).
67: Zijuan Hai, Yajie Bao, Qingqing Miao, Xiaoyi Yi, and Gaolin Liang*. Pyridine-Biquinoline-Metal Complexes for Sensing Pyrophosphate and Hydrogen Sulfide in Aqueous Buffer and in Cells. Anal. Chem.. 2015, 87 (5), 2678-2684 (DOI: 10.1021/ac504536q).
66: Shuang Liu, Anming Tang, Maolin Xie, Yundan Zhao, Jun Jiang, and Gaolin Liang*. Oligomeric Hydrogels Self-Assembled from Reduction-Controlled Condensation. Angew. Chem. Int. Ed.. 2015, 54 (12), 3639-3642 (DOI: 10.1002/anie.201409952).
65: Qingqing Miao, Ziye Wu, Zijuan Hai, Changlu Tao, Qingpan Yuan, Yadi Gong, Yafeng Guan, Jun Jiang,* and Gaolin Liang*. Bipyridine hydrogel for selective and visible detection and absorption of Cd2+. Nanoscale. 2015, 7, 2797 - 2804
64: Yue Yuan,# Hongbin Sun,# Shuchao Ge,# Mengjing Wang, Hongxin Zhao, Lin Wang, Linna An, Jia Zhang, Huafeng Zhang, Bing Hu*, Junfeng Wang*, Gaolin Liang*. Controlled Intracellular Self-assembly and Disassembly of 19F Nanoparticles for MR Imaging of Caspase 3/7 in Zebrafish. ACS Nano. 2015, 9 (1), 761-768 (DOI: 10.1021/nn5062657). #: Co-first author.
2014
63: Weijuan Wang,# Junchao Qian,# Anming Tang,# Linna An, Kai Zhong,* Gaolin Liang*. Using Magnetic Resonance Imaging to Study Enzymatic Hydrogelation. Anal. Chem.. 2014, 86, 5955-5961. (DOI: 10.1021/ac500967x). #: Co-first author.
62: Yue Yuan, Jia Zhang, Linna An, Qinjingwen Cao , Yun Deng, Gaolin Liang*. Oligomeric nanoparticles functionalized with NIR-emitting CdTe/CdS QDs and folate for tumor-targeted imaging. Biomaterials. 2014, 35, 7881-7886. (DOI: 10.1016/j.biomaterials.2014.05.071).
61: Shiyuan Li, Duyu Chen, Qingtong Zhou, Wei Wang, Lingfeng Gao, Jie Jiang, Haojun Liang, Yangzhong Liu, Gaolin Liang, Hua Cui*. A general chemiluminescence strategy for measuring aptamer-target binding and target concentration. Anal. Chem.. 2014, 86, 5559-5566. (DOI: 10.1021/ac501061c).
60: Xiaojing Wang, Qingqing Miao, Tingjie Song, Qingpan Yuan, Jinhao Gao, and Gaolin Liang*. Fluorescence switch for sequentially and selectively sensing copper (II) and L-histidine in vitro and in living cells. Analyst. 2014, 139, 3360-3364 (DOI: 10.1039/C4AN00410H).
59: Yue Yuan, Shenlong Jiang, Qingqing Miao, Jia Zhang, Mengjing Wang, Linna An, Qinjingwen Cao, Yafeng Guan, Qun Zhang*, and Gaolin Liang*. Fluorescent switch for fast and selective detection of mercury (II) ions in vitro and in living cells and a simple device for its removal. Talanta. 2014, 125, 204-209 (DOI: 10.1016/j.talanta.2014.02.063).
58: Linna An, M.Rehan H Shah Gilani, and Gaolin Liang*. Peptide-based Nanostructures for Cancer Diagnosis and Therapy. Curr. Med. Chem.. 2014, 21, 2453-2466.
57: Yue Yuan and Gaolin Liang*. A biocompatible, highly efficient click reaction and its applications. Org. Biomol. Chem., 2014, 12(6), 865-871 (DOI: 10.1039/C3OB41241E).
2013
56: Yue Yuan, Xijun Wang, Bin Mei, Dongxin Zhang, Anming Tang, Linna An, Xiaoxiao He, Jun Jiang*, and Gaolin Liang*. Labeling Thiols on Proteins, Living Cells, and Tissues with Enhanced Emission Induced by FRET. Sci. Rep., 2013. 3, 3523 (DOI: 10.1038/srep03523).
55: Fuqiang Wang, Ling Wang, Zhonghua Shi, and Gaolin Liang*. Comparative N-glycoproteomic and Phosphoproteomic Profiling of Human Placental Plasma Membrane between Normal and Preeclampsia Pregnancies with High-Resolution Mass Spectrometry. PLOS One. 2013, 8(11): e80480. (DOI: 10.1371/ journal.pone.0080480).
54: Fuqiang Wang, Zhonghua Shi, Ping Wang, Wei You, and Gaolin Liang*. Comparative proteome profile of human placenta from normal and preeclamptic pregnancies. PLOS One. 2013, 8(10): e78025. (DOI:10.1371/journal.pone.0078025).
53: Anming Tang, Bin Mei, Weijuan Wang, Wanglai Hu, Fang Li, Jun Zhou, Qing Yang, Hua Cui, Mian Wu, and Gaolin Liang*.FITC-quencher based, caspase 3-activatable nanoprobes for effectively sensing caspase 3 in vitro and in cells. Nanoscale. 2013, 5 (19), 8963-8967. (DOI: 10.1039/C3NR03339B ).
52: Rui Huang,# Xijun Wang,# Dingli Wang, Fang Liu, Bin Mei, Anming Tang, Jun Jiang*, and Gaolin Liang*. Multifunctional Fluorescent Probe for SequentialDetections of Glutathione and Caspase-3 in Vitro and in Cells. Anal. Chem.. 2013, 85, 6203-6207. DOI: 10.1021/ac4014012. #: Co-first author.
51:Yun Deng, Yufeng Luo, Linna An, M. Rehan H. Shah Gilani, and Gaolin Liang*. Covalently Conjugating Fluorescence Probes to Nanoparticles for Signal Enhancement. Chem. Lett.. 2013, 42 (10), 1157-1159. (DOI: 10.1246/cl.130424).
50: Anming Tang,# Weijuan Wang,# Bin Mei, Wanglai Hu, Mian Wu, and Gaolin Liang*. DEVD-Based Hydrogelator Minimizes Cellular Apoptosis Induction. Sci. Rep.. 2013, 3: 1848. (DOI: 10.1038/srep01848). #: Co-first author.
49: Fuqiang Wang, Ling Wang, Zhiyang Xu, and Gaolin Liang*. Identification and Analysis of Multi-protein Complexes in Placenta. PLOS One. 2013, 8 (4): e62988. (DOI:10.1371/journal.pone.0062988)
48: Longfei Liu, Qingqing Miao, and Gaolin Liang*. Quantim Dots as Multifunctional Materials for Tumor Imaging and Therapy. Materials. 2013, 6, 483-499. (DOI: 10.3390/ma6020483)
47: Yue Yuan, Jia Zhang, Mengjing Wang, Bin Mei, Yafeng Guan, and Gaolin Liang*. Detection of Glutathione in Vitro and in Cells by the Controlled Self-assembly of Nanorings. Anal. Chem.. 2013, 85, 1280-1284. (DOI: 10.1021/ac303183v)
46: Chunyan Cao, Huijing Liu, and Gaolin Liang*. Direct imaging furin-controlled intracellular condensation with two-photon laser microscope. Protocol Exchange. 2013, (DOI: 10.1038/protex.2013.005).
45: Chunyan Cao, Yingying Shen, Jiandong Wang,  Li Li*, and Gaolin Liang*. Controlled intracellular self-assembly of   gadolinium nanoparticles as smart molecular MR contrast agents. Sci. Rep.. 2013, 3, 1024. (DOI:  10.1038/srep01024).

2012
44: Mengjing Wang, Yue Yuan, and Gaolin Liang*. "Click Chemistry" for Molecular Imaging. Curr. Mol. Imaging. 2012, 1, 87-95. (DOI: 10.2174/2211212700123115552).
43: Xingyi Li, Chengbiao Yang, Zhaoliang Zhang, Zhidan Wu, Yun Deng, Gaolin Liang, Zhimou Yang, and Hao Chen*. Folic acid as a versatile motif to construct molecular hydrogelators through conjugations with hydrophobic therapeutic agents. J. Mater. Chem.. 2012, 22 (41), 21838-21840. (DOI: 10.1039/C2JM35329F)
42:  Qingqing Miao, Xiaoyu Bai, Yingying Shen, Bin Mei, Jinhao Gao, Li Li, and Gaolin Liang*. Intracellular self-assembly of nanoparticles for enhancing cell uptake. Chem. Commun.. 2012, 48 (78), 9738-9740.    (DOI: 10.1039/C2CC34899C).
41:  Xiaojing Wang, Qian Li, Yue Yuan, Bin Mei, Rui Huang, Ying Tian, Jing Sun, Chunyan Cao, Guangming Lu, and Gaolin Liang*. New method for effectively and quantitatively labeling cysteine residues on chicken eggshell membrane. Org. Biomol. Chem. 2012, 10, 8082-8086. (DOI: 10.1039/C2OB26279G).
40:  Yue Yuan, Jia Zhang, Gaolin Liang*, Xiurong Yang*.  Rapid fluorescent detection of neurogenin3 by CdTe quantum dotaggregation. Analyst. 2012, 137, 1775-1778. (DOI: 10.1039/C2AN16166D)
39: Xiaoli Zhang, Xinlei Chu, Ling Wang, Huaimin Wang, Gaolin Liang, Jinxiu Zhang, Jiafu Long*, and Zhimou Yang*.   Rational Design of A Tetrameric Protein to Enhance Interactions Between Self-assembled Fibers Confers Molecular Hydrogels. Angew. Chem. Int. Ed.. 2012, 51, 4388-4392. (DOI: 10.1002/anie. 201108612)
38: Yue Chen, and Gaolin Liang*. Enzymatic self-assembly of nanostructures for theranostics. Theranostics. 2012; 2(2):  139-147. (DOI: 10.7150/thno.3696).
2011
37:  Yun Deng, Shuang Liu, Kun Mei, Anming Tang, Chunyan Cao, and Gaolin Liang*. Multifunctional small molecule for  controlled assembly of oligomeric nanoparticles and crosslinked polymers. Org. Biomol. Chem..   2011, 9, 6917-6919. (DOI: 10.1039/C1OB06132A)
36:  Chunyan Cao, Yue Chen, Fangzhou Wu, Yun Deng, and Gaolin Liang*. Caspase-3 controlled assembly of       nanoparticles for fluorescence turn on. Chem. Commun.. 2011, 47, 10320-10322. (DOI: 10.1039/C1CC14112K)
35:  Gaolin Liang, John Ronald, Yuanxin Chen, Deju Ye, Prachi Pandit, Manlung Ma,  Brian Rutt, and Jianghong Rao.    Controlled Self-Assembling of Gadolinium Nanoparticles as "Smart" Molecular Magnetic Resonance Imaging Contrast     Agents. Angew. Chem. Int. Ed.. 2011, 50: 6283-6285. (DOI: 10.1002/anie.201007018)
34: Deju Ye, Gaolin Liang, Manlung Ma, and Jianghong Rao. Controlling intracellular macrocyclization for the imaging of protease activity. Angew. Chem. Int. Ed.. 2011, 50: 2275-2279. (DOI: 10.1002/anie.201006140)

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